Nonclinical Safety Computational Toxicologist, Distinguished Scientist

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Job Title: Nonclinical Safety Computational Toxicologist, Distinguished Scientist

Company Name:	Johnson & Johnson
Location:	Spring House, PA
Position Type:	Full Time
Post Date:	02/25/2026
Expire Date:	04/03/2026
Job Categories:	Healthcare, Other, Science, Medical

Job Description

Nonclinical Safety Computational Toxicologist, Distinguished Scientist
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at <a target="_blank" href="https://www.jnj.com">jnj.com</a>As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.Job Function: Discovery & Pre-Clinical/Clinical DevelopmentJob Sub Function: Nonclinical SafetyJob Category:Scientific/TechnologyAll Job Posting Locations:San Diego, California, United States of America, Spring House, Pennsylvania, United States of AmericaJob Description:Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.Learn more at https://www.jnj.com/innovative-medicineWe are searching for the best talent for a Nonclinical Safety Computational Toxicologist, Distinguished Scientist, in Spring House, PA or La Jolla, CA.Purpose: The Nonclinical Safety Computational Toxicologist, Distinguished Scientist, in the Preclinical Sciences and Translational Safety (PSTS) organization within J&J Research & Development, will lead application of data science and machine learning (ML) methodologies to the assessment of nonclinical safety and generation of submissions deliverables. This role emphasizes using next generation data science tools and systems to guide decisions, improve efficiency, and ensure regulatory compliance throughout the drug discovery and development pipeline.You will be responsible for:<ul><li>Global lead for nonclinical safety and submissions data science and ML initiatives for Department of Nonclinical Safety & Submissions (NCSS), ensuring strong project management and collaboration with partners within and external to PSTS (eg IT Data Science), and alignment of data science/ML initiatives with overall strategic project goals of PSTS.</li><li>Identify, assess, recommend, and develop proposals for new data science opportunities to drive next generation nonclinical safety tools, submissions, and strategy to predict, derisk, and/or understand potential toxicities and production of high quality, compliant submission documents.</li><li>Create innovative visualizations and user interfaces to help scientists access & interpret data and translate complex data from diverse sources into actionable insights.</li><li>Support development of new approach methodologies (NAMs) and computational methods to achieve 3Rs in drug development.</li><li>Understand specific business needs and translate the scientific and regulatory challenges and opportunities into smarter data innovation solutions, and drive validation strategies for model performance.</li><li>Drive rollout, re-enforcement, monitoring, and continuous improvement of implemented data science initiatives.</li><li>Mentor and provide training on the use and utility of predictive ML approaches in drug safety and submissions. </li></ul>Qualifications / Requirements:Education:<ul><li>Minimum of PhD in biomedical sciences, toxicology, pharmacology, computational biology, bioinformatics, data science, or advanced degree in a relevant field is required.</li></ul>Experience/Skills:<ul><li>A minimum of 8 years of relevant experience is required in nonclinical drug development and submissions supporting diverse modalities, geographies, and therapeutic areas.</li><li>Extensive experience (6+ years) in data science with a focus on machine learning, predictive modeling, data mining, statistics, deep learning, and data visualization/dashboarding frameworks.</li><li>Proven track record of implemented data science tools and innovation.</li><li>Exceptional interpersonal skills, diplomacy and negotiating skills, troubleshooting skills and ability to work effectively in a collaborative environment.</li><li>Strong leadership, project management, communication, and interpersonal skills to lead and influence across functions.</li><li>Strong change/process management and organizational skills</li><li>Knowledge of GLP, SEND, and data security/integrity standards</li></ul>Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (ra-employeehealthsup@its.jnj.com) or contact AskGS to be directed to your accommodation resource.Required Skills: Preferred Skills:Consulting, Design Mindset, Drug Discovery Development, EHS Compliance, Emergency Planning, Performance Measurement, Process Hazard Analysis (PHA), Process Optimization, Program Management, Regulatory Affairs Management, Research and Development, Risk Management, Safety Audits, Safety Investigations, Safety-Oriented, Scientific Research, Stakeholder Engagement, Strategic Thinking, Technical Writing The anticipated base pay range for this position is :$164,000.00 - $282,900.00Additional Description for Pay Transparency:Subject to the terms of their respective policies and date of hire, employees are eligible for the following time off benefits: Vacation –120 hours per calendar year Sick time - 40 hours per calendar year; for employees who reside in the State of Colorado –48 hours per calendar year; for employees who reside in the State of Washington –56 hours per calendar year Holiday pay, including Floating Holidays –13 days per calendar year Work, Personal and Family Time - up to 40 hours per calendar year Parental Leave – 480 hours within one year of the birth/adoption/foster care of a child Bereavement Leave – 240 hours for an immediate family member: 40 hours for an extended family member per calendar year Caregiver Leave – 80 hours in a 52-week rolling period10 days Volunteer Leave – 32 hours per calendar year Military Spouse Time-Off – 80 hours per calendar year Please use the following language: For additional general information on Company benefits, please go to: - https://www.careers.jnj.com/employee-benefits

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